Areas of research
The OHTN Cohort Study research program focuses on four key areas of research
- Social and Behavioral Research
- Clinical Research
- HIV Prevention Research
- Health Services Research
Contact the OCS Study Coordinator at [email protected] if interested in a publication that is not available as a full text online.
How can I access OHTN Cohort Study data? The OHTN Cohort Study encourages new and past collaborators to submit proposals for analysis projects. The following 5 steps are required to complete the Research Application Process (RAP). A more detailed description of the Research Approval Process is set out in the Terms of Reference.
Step 1: Research idea
We know that developing a research idea can be challenging especially when one is not familiar with the scope and limitations of the OHTN Cohort Study. In an effort to support collaborators to develop focused research questions we ask that they submit an OHTN Cohort Study Concept Sheet to the OHTN Cohort Study research coordinator. Following review and approval of an OHTN Cohort Study Concept Sheet, collaborator(s) may submit a “Data Scan Request” form to obtain aggregate-level OHTN Cohort Study data to assess study feasibility.
Step 2: Developing an OCS Project Proposal
Collaborators will be encouraged to complete an OCS Project Proposal only after the review and approval of an OCS Concept Sheet. All Research Project Proposals must contain the information set out in the OCS Research Proposal Checklist, in particular, whether OHTN Cohort Study data are sought in Standard Release or Conditional Release format. It’s important to note that the Research Project Proposal must be eligible for implicit approval by the research ethics board (REB) of the University of Toronto or have obtained research ethics board (REB) review and approval from the University of Toronto.
Step 3: OHTN Cohort Study: Scientific Review of Research Project Proposals
The OHTN Cohort Study Scientific Steering Committee conducts scientific review to ensure that the research objectives and the analytical plan of each proposal are scientifically feasible and methodologically sound. The Scientific Steering Committee will also assess the necessity of each data element requested in the Research Project proposal to assess whether the proposal presents a risk of residual disclosure and, if so, to recommend how any such risk may be addressed. A Research Project Proposal that has obtained research ethics board (REB) approval from the University of Toronto may be exempted from OHTN’s scientific review by the OHTN Cohort Study Principal Investigator. Following scientific review, the Scientific Steering Committee may recommend the Research Project Proposal for approval as proposed or with revision(s). A proposal will proceed for review by the Governance Committee if and as approved by the Scientific Steering Committee.
Step 4: Community Review by OHTN Cohort Study Governance Committee
The purpose of community review by the Governance Committee is to review each Research Project Proposal following successful scientific review for ethical considerations and for consistency with the OHTN and OHTN Cohort Study’ guiding principles. The Governance Committee may, approve the Research Project Proposal as proposed or with comments and/or revision(s). Once approved, a Research Project Proposal is a “Research Project”.
Step 5: Release of OHTN Cohort Study Data
The OHTN will disclose to Research Project PIs (or their Research Project Team members) only that OHTN Cohort Study Data which has been approved for collection, use and/or disclosure in accordance with steps 3 and 4 above. The OHTN will disclose approved OHTN Cohort Study Data in a release format that provides OHTN Cohort Study participants with the greatest possible protection of their privacy and confidentiality while still meeting the administrative and/or research purposes for which the collection, use and/or disclosure of OHTN Cohort Study data have been authorized.
Scientific steering committee
- Sergio Rueda, Chair
- Barry Adam
- Anita Benoit
- Ann Burchell, Co-Investigator
- Curtis Cooper
- Trevor Hart
- Sean Hillier
- Mona Loutfy
- Kelly O’Brien
- David Brennan
- Lawrence Mbuagbaw
- Lance McCready
- Pierre Giguere
OHTN Cohort Study Questionnaire
The OHTN Cohort Study questionnaire was introduced in 2007 to augment the scope of data collected through clinical chart extraction. Participants are requested to complete an interviewer administered questionnaire yearly. The questionnaire is modular allowing the OHTN Cohort Study the flexibility to ask different questions every year. The base interview module takes approximately 60 minutes to complete. Each year there may be additional sections which are added up to a time maximum of 60 minutes. Participant responses are collected electronically, with no identifying information.
The list of current topics are here.